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Isolated extramedullary relapse of acute lymphoblastic leukemia in the breast of an adolescent girl: radiologic findings and discussion.
Kumar PR, Grossman Z, Scorza L, Khoury T, Nayyar R.
Department of Radiology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY, 14263, USA, prasanna.kumar@roswellpark.org.
We report a case of isolated extramedullary leukemia relapse in the breast of an adolescent girl. A 13-year-old girl with acute lymphoblastic leukemia in remission, post-chemotherapy and unrelated cord blood transplant, presented with a breast lump. US and mammography demonstrated a large hypervascular heterogeneous mass. Examination of tissue provided by US-guided core biopsy confirmed focal leukemic relapse. US is a commonly used diagnostic tool in children and adolescents with a breast mass, for both characterization and guided biopsy.
Pediatr Radiol. 2010 Feb 5.
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